Core B Complex supports essential body functions through methylation, a vitamin-dependent biochemical process crucial for mental and physical health. Methylation helps regulate gene expression, repair DNA continually, and maintain cellular health. It occurs billions of times each second, but when it slows, DNA damage increases. Beyond DNA repair, methylation is vital for producing neurotransmitters, balancing homocysteine for heart health, and recycling molecules needed for detoxification and managing inflammation. It also supports energy metabolism, immune response, and nerve cell function.

Nutrient deficiencies such as folate, B2, B6, and B12 can hinder proper methylation, and certain medications may further deplete these vital nutrients. Core B Complex delivers high-concentration folate as Quatrefolic®—the biologically active 5-MTHF form—along with trimethylglycine, and the essential methylation vitamins B2, B6, and B12 (methylcobalamin). This blend of methyl donors enhances DNA repair, maintains homocysteine levels, supports neurotransmitter production, balances hormones, and optimizes detoxification processes.


Equivalent to Methyl CPG. May be substituted without notice, containing the same ingredients under the Ortho Molecular label.