Take 1 soft gel capsule two times per day or as recommended by your health care professional.

Research

Discovered by Dr. Hiroyuki Sumi, nattokinase has been shown to help keep blood flowing normally. In a study on the effect of nattokinase on blood flow in the common carotid artery, animals treated with nattokinase regained 62% of their blood flow, while animals given plasmin regained 15.8%, and 0% was regained with elastase. Researchers concluded that in this in vivo model, the circulation supporting activity of nattokinase was stronger than that of plasmin or elastase. Other in vitro studies revealed nattokinase caused a significant, dose-dependent decrease of red blood cell aggregation and low-shear viscosity, effects which were evident at concentrations similar to those achieved with in vivo animal trials. Researchers have also confirmed the presence of unique compounds that inhibit angiotensin converting enzymes (ACE) within nattokinase, which supports healthy arterial blood pressure. In a recent eight-week, randomized, double-blind, placebo-controlled trial of 73 subjects given oral nattokinase supplementation, a healthy effect on blood pressure and blood flow was seen.

Nattokinase