Broad-Range Specificity Immunoglobulins
Research has shown that IgG can be effective in neutralizing microorganisms found in the gastrointestinal tract. Colostrum not only includes high quantities of IgG but also several factors that may positively impact the immune system. Many studies note the use of bovine colostrum to enhance passive immunity to prevent immune challenges, especially when entering by way of the gastrointestinal tract.
Lactoferrin
Lactoferrin, which is naturally occurring in IgG Protect, is an iron-binding glycoprotein that facilitates iron absorption. Lactoferrin modulates cytokine release, and its receptors have been found on many immune cells, including lymphocytes, monocytes, macrophages and platelets.
Proline-Rich Peptides (PRPs)*
PRPs are signaling peptides produced by activated macrophages and the T cells that control the production of all cytokines. PRPs have the unique ability to modulate the immune system by increasing activity level in case of certain challenges and decreasing activity level when health is maintained. PRPs are the main regulators of cell protein synthesis and convey appropriate cell functions.
Growth Factors*
Growth factors in colostrum extract, such as insulin-like growth factor-1 and 2 (IGF-1 and IGF-2), and transforming growth factor-beta 2 (TGF-β2) function to stimulate normal epithelial tissue growth in addition to upregulating B-cell growth and differentiation to increase antibody production by the body. They have also been shown to affect rates of protein synthesis, protein degradation and DNA synthesis. In addition, TGF-β2 may be beneficial in reducing gut permeability and enhancing cell rejuvenation.
Sialic Acid*
Sialic acid is an essential component of glycoproteins, which may function to influence brain growth and enhance learning ability and memory formation. Sialic acid has been shown to assist in enhancing synaptic pathways. It may also assist in immune regulation when necessary.
*Not standardized in colostrum extracts
