Hormones (especially estrogen) are critically important in human development and tissue repair. However, estrogen’s proliferative effects must be balanced and controlled for optimal health. Therefore, to ensure proper hormonal balance, estrogen synthesis and detoxification should be supported. Estrogen has several downstream metabolites, of which some are beneficial while others possess potentially harmful biological activity. By keeping hormones in balance and ensuring the body can process estrogen properly, cruciferous vegetable metabolites (i.e., I3C and DIM) work together to maintain cellular health.

EstroDIM® is a targeted supplement that combines the synergistic benefits of the cruciferous vegetable metabolites indole-3-carbinol (I3C) and 3-3’-diindolylmethane (DIM) to support balanced estrogen metabolism. Formulating I3C and DIM together creates the ideal combination of beneficial metabolites that work together to support estrogen balance, breast and prostate health.


Equivalent to DIM Plus. May be substituted without notice, containing the same ingredients under the The James Clinic label.

1 capsule per day or as recommended by your health care professional.

Orders are processed within 1–3 business days, depending on availability and credit card authorization. After processing, your order will ship at the speed you selected during checkout. Please note we don’t ship on weekends or major holidays, and shipping timelines may be affected by the carrier.
Once your package is scanned by the carrier, tracking information will be sent to you by email or text message. Please allow 24–48 hours for tracking details to update.

While we ensure satisfaction, we don't accept returns on any products or supplements. If you have any concerns, please email us at shop@jamesclinic.com, and we'll work to resolve them with you.