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The James Clinic
Designed to support mental clarity, memory, mood, and sleep. Each serving delivers a potent 2 grams of concentrated magnesium L-threonate for a multidimensional approach to maintaining and improving cognitive function.
Magnesium is a crucial mineral involved in over 300 enzymatic reactions in the body, essential for brain health, neurotransmitter synthesis, and maintaining the blood-brain barrier.
Unfortunately, nearly half of the U.S. population consumes less than the recommended amount. Factors such as aging, health conditions, and lifestyle choices can further deplete magnesium levels.
Magnesium L-threonate, a unique form developed by MIT researchers, is the only compound proven to effectively raise brain magnesium levels, supporting neuroplasticity, mental focus, memory, mood, and a healthy sleep-wake cycle while helping to reduce occasional stress.
Equivalent to Mag Threonate. May be substituted without notice, containing the same ingredients under the Ortho Molecular label.
Take 2 capsules per day or as recommended by your health care professional.
Sleep Quality
Poor sleep affects 62% of adults worldwide. Insufficient magnesium intake and poor sleep have been correlated in several studies. Some mechanisms to explain the connection of poor sleep with inadequate magnesium are the ability of magnesium to bind gamma-aminobutyric acid (GABA) receptors, attenuation of the stress response or its role as a cofactor in melatonin synthesis.
Mental-Emotional Health
A 2023 survey reports that 49% of adults in the United States report frequent stress. Symptoms of low mood and nervousness can occur independently of stress but are often experienced at the same time. In the brain, magnesium supports mood and emotional health by acting as a cofactor for the synthesis of dopamine and serotonin, inhibiting the release of excitatory glutamate and binding calming GABA receptors.
Memory and Concentration
Memory and mental focus are common patient concerns. In an animal model, magnesium L-threonate was found to increase the synaptic density and function of neurons in the brain. A decline in neuronal synapses, their function and consequent atrophy of the brain are associated with impaired cognition, a process that increases with age. In a study of older adults with memory concerns, those that received 1.5 to 2 g of magnesium L-threonate daily demonstrated improvement in executive function, working (short-term) memory and episodic memory.
Magnesium (as Magnesium L-Threonate), Magnesium L-Threonate (Magtein®)
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